Exact Cause Unknown

Idiopathic Condition

Possible Hereditary / Familial Predisposition

Abnormal Fibroblast Activity

Genetically Determined Fibroblast Response

Altered Collagen Metabolism

↓ Reduced Collagen Degradation

↓ Increased Collagen Accumulation

Excessive Connective Tissue Deposition

Gingival Enlargement

Plaque-Induced Inflammation

(Aggravating factor, not primary cause)