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Neuron releasing serotonin
Ca²⁺ ion channel
K⁺ ion channel
5-HT1A receptor (serotonin ligand)
G-proteins (Gi, Go)
Adenyl cyclase
cAMP
SERT (serotonin transporter) SSRI inhibit SERT
Neuron receiving serotonin
Ca²⁺ is needed for neurotransmitter release
Cell surface is polarized
inhibits
activate
cAMP reduced
Secondary messenger
SSRI inhibit SERT
inhibits
SSRI
by dino
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