Livoa LogoLivoa
Immune & Anti-Invasive Effects
Cell Cycle Arrest
G1
S
G2M
M
Blocked by: p5↑, p21↑, Cyclin↓, CDK↓
● Phytochemicals: Flavonoids, Phenolic Acids
Signaling Pathway Modulation
PI3K/AKT Pathway
Growth Factor Receptor
PISI
PDK1
AKT
● Inhibited by: Flavonoids, Carotenoids
MAPK/NF-κB Pathways
MAPK
MAPK
JNF-κB
IKK
● Modulated by: Flavonoids, Carotenoids, Phenolic Acids
● Flavonoids (Blue) ● Carotenoids (Green) ● Phenolic Acids (Orange)
Phytchemacias: Rebalancing Control
Immunostimulation
Anti-Invasion
Lymphocyte
Proliferation
Macrophage
Phagocytosis
Macrophage
Phagocytosis
Cancer Cells
NK Cell Cytotoxicity
Cell migration
Invasion
Tumor growth
Stimulated by:
Polysaccharides
(HRWP-A)
Inhibited by:
Fatty Acids (Omega Fatty Acids) &
Polysaccharides (HRWP-A)
Lymphocyte
Proliferation
Macrophage
Phagocytosis
Macrophage
Phagocytosis
Cancer
Cells
NK Cell
Cytotoxicity
Macrophage
Phagocytosis
Stimulated by:
Polysaccharides (HRWP-A)
Anti-Invasion
Inhibited Cell
Migration & Invasion
Inhibited Tumor Growth
Inhibited by:
Fatty Acids (Omega Fatty Acids) &
Polysaccharides (HRWP-A)

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