PND 0: Asymptomatic (Genetic Mutation Detected)

PND I: Sensory Disturbance (Preserved Walking Capacity)

PND II: Unassisted Walking (With Difficulty)

Transient Events Management

PND IIIA: Walking Aid Required (One Stick/Crutch)

Stabilized Disease (Under Treatment)

PND IIIB: Walking Aid Required (Two Sticks/Crutches)

PND IV: Severe Disability (Wheelchair/Bedridden)

Terminal Care (Severe Disability and Organ Failure)

Cardiomyopathy Management

Onset of sensory disturbances

Walking difficulty begins

Requires one stick or crutch

Requires two sticks or crutches

Wheelchair-bound or bedridden

NT-proBNP ≥ 3000: Cardiomyopathy

Return to severe disability

Progression to terminal care

Progression to terminal care

Progression to terminal care

Progression to terminal care

Progression to terminal care

Progression to terminal care

Transient events like pain flare-ups

Return to previous stage

Treatment effect can stabilize

Further progression

Effective management

Effective management